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pentobarbital will reduce the level or influence of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.Contraindicated (1)pentobarbital decreases amounts of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can lessen panobinostat degrees